- Doctor Doom (Victor Von Doom) first appeared in Fantastic Four #5 in July, 1962
- Spider-Man (Peter Parker) (pictured) recently revealed his secret identity at a press conference in the new Civil War series
- Black Panther (T'Challa) and Storm recently married, following a proposal during House of M
- X-23 was originally made for the animated TV series X-Men: Evolution, but first appeared in comics in the NYX series and has since got her own comic
- Nocturne (TJ Wagner) is the daughter of Nightcrawler and Scarlet Witch from an alternate timeline